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Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

The expression of CD45RA is generally associated with naive T cells. However, a subset of effector memory T cells re-expresses CD45RA (termed TEMRA) after antigenic stimulation with unknown molecular characteristics and functions. CD4 TEMRA cells have been implicated in protective immunity against p...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Babor, Mariana, Lane, Jerome, Schulten, Veronique, Patil, Veena S., Seumois, Grégory, Rosales, Sandy L., Fu, Zheng, Picarda, Gaelle, Burel, Julie, Zapardiel-Gonzalo, Jose, Tennekoon, Rashika N., De Silva, Aruna D., Premawansa, Sunil, Premawansa, Gayani, Wijewickrama, Ananda, Greenbaum, Jason A., Vijayanand, Pandurangan, Weiskopf, Daniela, Sette, Alessandro, Peters, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684192/
https://www.ncbi.nlm.nih.gov/pubmed/29133794
http://dx.doi.org/10.1038/s41467-017-01728-5