Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells

Renal angiomyolipomas (AML) contain an admixture of clonal tumour cells with features of several different mesenchymal lineages, implying the existence of an unidentified AML neoplastic stem cell. Biallelic inactivation of TSC2 or TSC1 is believed to represent the driving event in these tumours. Her...

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Detalles Bibliográficos
Autores principales: Gonçalves, Ana Filipa, Adlesic, Mojca, Brandt, Simone, Hejhal, Tomas, Harlander, Sabine, Sommer, Lukas, Shakhova, Olga, Wild, Peter J., Frew, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684212/
https://www.ncbi.nlm.nih.gov/pubmed/29133867
http://dx.doi.org/10.1038/s41467-017-01514-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684212/
https://www.ncbi.nlm.nih.gov/pubmed/29133867
http://dx.doi.org/10.1038/s41467-017-01514-3

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