Cargando…

Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells

Renal angiomyolipomas (AML) contain an admixture of clonal tumour cells with features of several different mesenchymal lineages, implying the existence of an unidentified AML neoplastic stem cell. Biallelic inactivation of TSC2 or TSC1 is believed to represent the driving event in these tumours. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gonçalves, Ana Filipa, Adlesic, Mojca, Brandt, Simone, Hejhal, Tomas, Harlander, Sabine, Sommer, Lukas, Shakhova, Olga, Wild, Peter J., Frew, Ian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684212/ https://www.ncbi.nlm.nih.gov/pubmed/29133867 http://dx.doi.org/10.1038/s41467-017-01514-3

Ejemplares similares

Combined Vhl, Trp53 and Rb1 mutation causes clear cell renal cell carcinoma in mice
por: Harlander, Sabine, et al.
Publicado: (2017)

Cdk4 functions in multiple cell types to control Drosophila intestinal stem cell proliferation and differentiation
por: Adlesic, Mojca, et al.
Publicado: (2016)

Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma
por: Hoefflin, Rouven, et al.
Publicado: (2021)

Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma
por: Zhao, Dan-Dan, et al.
Publicado: (2019)

Mouse genetic background influences whether Hras(G12V) expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma
por: Brandt, Laura P., et al.
Publicado: (2018)

Renal angiomyolipoma with bleeding
por: Muttarak, M, et al.
Publicado: (2007)

Ruptured Renal Angiomyolipoma
por: Azzi, Sébastien, et al.
Publicado: (2022)

Renal angiomyolipoma with renal vein extension
por: Kassimi, Mariam, et al.
Publicado: (2021)

Renal angiomyolipoma with epithelial cyst
por: Varshney, Bharti, et al.
Publicado: (2021)

Renal Epithelioid Angiomyolipoma in Children
por: Mahajan, Dhruv, et al.
Publicado: (2021)

Integrated Metabolomic and Transcriptomic Analysis of Modified Nucleosides for Biomarker Discovery in Clear Cell Renal Cell Carcinoma
por: Mohl, Daniel A., et al.
Publicado: (2023)

A Case of Angiomyolipoma Arising in the Tongue
por: Yura, Shinya, et al.
Publicado: (2011)

Renal angiomyolipoma with renal vein thrombosis: an incidental finding
por: Melo Abreu, Elisa, et al.
Publicado: (2016)

Wunderlich syndrome with spontaneous renal hemorrhage into renal angiomyolipoma
por: Bhatty, Tanweer, et al.
Publicado: (2020)

Oncogenic Hras(G12V) expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma
por: Brandt, Laura P., et al.
Publicado: (2017)

Managing a massive renal angiomyolipoma
por: Gupta, Sanjana, et al.
Publicado: (2012)

Renal Angiomyolipoma: The Good, the Bad, and the Ugly
por: Vos, Nicolas, et al.
Publicado: (2018)

The Risks of Renal Angiomyolipoma: Reviewing the Evidence
por: Seyam, Raouf M., et al.
Publicado: (2017)

Postembolization rupture of a renal angiomyolipoma
por: Veiga, Carlos, et al.
Publicado: (2022)

Embolization of Ruptured Renal Angiomyolipoma in Puerpera
por: Góes Junior, Adenauer Marinho de Oliveira, et al.
Publicado: (2019)

Large renal angiomyolipomas in tuberous sclerosis
por: Esson, G, et al.
Publicado: (2023)

Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition
por: Catalano, Antonella, et al.
Publicado: (2021)

Fat‐poor leiomyomatous angiomyolipoma arising from renal parenchyma negative for HMB‐45: A case report
por: Kobayashi, Yasuyuki, et al.
Publicado: (2022)

Huge Renal Angiomyolipoma Mimicking a Renal Cell Carcinoma: A Case Report
por: Devasilpa Raju, Poosapati D, et al.
Publicado: (2022)

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis
por: Schönenberger, Désirée, et al.
Publicado: (2016)

The independent indicators for differentiating renal cell carcinoma from renal angiomyolipoma by contrast-enhanced ultrasound
por: Cao, Hongli, et al.
Publicado: (2020)

Surgical management of haemorrhaging renal angiomyolipoma in pregnancy
por: Preece, P., et al.
Publicado: (2015)

CT-imaging features of renal epithelioid angiomyolipoma
por: Liu, Ying, et al.
Publicado: (2015)

Urgent arterial embolization of ruptured renal angiomyolipoma
por: Kervancioglu, Selim, et al.
Publicado: (2015)

Tuberous sclerosis with bilateral giant renal angiomyolipomas
por: Kumar, Suresh, et al.
Publicado: (2016)

Transarterial Embolization of a Ruptured Renal Angiomyolipoma
por: Taki, Yasuhiro, et al.
Publicado: (2017)

An update on recent developments in rupture of renal angiomyolipoma
por: Wang, Chenyang, et al.
Publicado: (2018)

Unilateral giant renal angiomyolipoma and pulmonary lymphangioleiomyomatosis
por: de Campos, Fernando Peixoto Ferraz, et al.
Publicado: (2013)

Renal sinus angiomyolipoma: A rare case
por: Gupta, Abhimanyu, et al.
Publicado: (2020)

Everolimus in Invasive Malignant Renal Epithelioid Angiomyolipoma
por: Guo, Gang, et al.
Publicado: (2021)

Use of microspheres in embolization for unruptured renal angiomyolipomas
por: Shimohira, Masashi, et al.
Publicado: (2021)

Giant renal angiomyolipoma: A case report
por: Al-Hajjaj, Maher
Publicado: (2021)

Spectrum of Presentations and Management Strategies in Renal Angiomyolipoma
por: Khaddam, Sinan, et al.
Publicado: (2022)

Pulmonary lymphangioleiomyomatosis with an associated giant renal angiomyolipoma
por: John, Jeff, et al.
Publicado: (2022)

Exceptional Extension of Benign Angiomyolipoma in the Renal Vein
por: Lepot, Darius, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gt1ulctqcg0n050ghajgs4qff0