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Two-step process for disassembly mechanism of proteasome α7 homo-tetradecamer by α6 revealed by high-speed atomic force microscopy

The 20S proteasome is a core particle of the eukaryotic proteasome responsible for proteolysis and is composed of layered α and β hetero-heptameric rings. The α7 subunit, which is one of components of the α ring, is known to self-assemble into a double-ringed homo-tetradecamer composed of two layers...

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Detalles Bibliográficos
Autores principales:	Kozai, Toshiya, Sekiguchi, Taichiro, Satoh, Tadashi, Yagi, Hirokazu, Kato, Koichi, Uchihashi, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684232/ https://www.ncbi.nlm.nih.gov/pubmed/29133893 http://dx.doi.org/10.1038/s41598-017-15708-8

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