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Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy

AIM: To evaluate the configuration of the anterior chamber angle quantitatively and study the morphological changes in the eye with ultrasound biomicroscopy (UBM) in primary angle closure glaucoma (PACG) patients after laser peripheral iridotomy (LPI). MATERIALS AND METHODS: A total of 185 eyes of 1...

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Autores principales: Mansoori, Tarannum, Balakrishna, Nagalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684238/
https://www.ncbi.nlm.nih.gov/pubmed/29151682
http://dx.doi.org/10.5005/jp-journals-10028-1230
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author Mansoori, Tarannum
Balakrishna, Nagalla
author_facet Mansoori, Tarannum
Balakrishna, Nagalla
author_sort Mansoori, Tarannum
collection PubMed
description AIM: To evaluate the configuration of the anterior chamber angle quantitatively and study the morphological changes in the eye with ultrasound biomicroscopy (UBM) in primary angle closure glaucoma (PACG) patients after laser peripheral iridotomy (LPI). MATERIALS AND METHODS: A total of 185 eyes of 185 PACG patients post-LPI and 126 eyes of 126 normal subjects were included in this prospective study. All subjects underwent complete ophthalmic evaluation, A-scan biometry, and UBM. The anterior segment and angle parameters were measured quantitatively and compared in both groups using Student’s t-test. RESULTS: The PACG patients had shorter axial length, shallower central anterior chamber depth anterior chamber depth (ACD), and anteriorly located lens when compared with normal subjects. Trabecular iris angle (TIA) was significantly narrow (5.73 ± 7.76°) in patients with PACG when compared with normal subjects (23.75 ± 9.38°). The angle opening distance at 500 pm from scleral spur (AOD 500), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), and iris-zonule distance (IZD) were significantly shorter in patients with PACG than in normal subjects (p < 0.0001). The iris lens angle (ILA), scleral-iris angle (SIA), and scleral-ciliary process angle (SCPA) were significantly narrower in patients with PACG than in normal subjects (p < 0.0001). The iris-lens contact distance (ILCD) was greater in PACG group than in normal (p = 0.001). Plateau iris was seen in 57/185 (30.8%) of the eyes. Anterior positioned ciliary processes were seen in 130/185 eyes (70.3%) of eyes. CONCLUSION: In PACG patients, persistent apposition angle closure is common even after LPI, which could be due to anterior rotation of ciliary body and plateau iris and overcrowding of anterior segment due to shorter axial length and relative anterior lens position. How to cite this article: Mansoori T, Balakrishna N. Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy. J Curr Glaucoma Pract 2017;11(3):86-91.
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spelling pubmed-56842382017-11-17 Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy Mansoori, Tarannum Balakrishna, Nagalla J Curr Glaucoma Pract Original Article AIM: To evaluate the configuration of the anterior chamber angle quantitatively and study the morphological changes in the eye with ultrasound biomicroscopy (UBM) in primary angle closure glaucoma (PACG) patients after laser peripheral iridotomy (LPI). MATERIALS AND METHODS: A total of 185 eyes of 185 PACG patients post-LPI and 126 eyes of 126 normal subjects were included in this prospective study. All subjects underwent complete ophthalmic evaluation, A-scan biometry, and UBM. The anterior segment and angle parameters were measured quantitatively and compared in both groups using Student’s t-test. RESULTS: The PACG patients had shorter axial length, shallower central anterior chamber depth anterior chamber depth (ACD), and anteriorly located lens when compared with normal subjects. Trabecular iris angle (TIA) was significantly narrow (5.73 ± 7.76°) in patients with PACG when compared with normal subjects (23.75 ± 9.38°). The angle opening distance at 500 pm from scleral spur (AOD 500), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), and iris-zonule distance (IZD) were significantly shorter in patients with PACG than in normal subjects (p < 0.0001). The iris lens angle (ILA), scleral-iris angle (SIA), and scleral-ciliary process angle (SCPA) were significantly narrower in patients with PACG than in normal subjects (p < 0.0001). The iris-lens contact distance (ILCD) was greater in PACG group than in normal (p = 0.001). Plateau iris was seen in 57/185 (30.8%) of the eyes. Anterior positioned ciliary processes were seen in 130/185 eyes (70.3%) of eyes. CONCLUSION: In PACG patients, persistent apposition angle closure is common even after LPI, which could be due to anterior rotation of ciliary body and plateau iris and overcrowding of anterior segment due to shorter axial length and relative anterior lens position. How to cite this article: Mansoori T, Balakrishna N. Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy. J Curr Glaucoma Pract 2017;11(3):86-91. Jaypee Brothers Medical Publishers 2017 2017-10-27 /pmc/articles/PMC5684238/ /pubmed/29151682 http://dx.doi.org/10.5005/jp-journals-10028-1230 Text en Copyright © 2017; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Original Article
Mansoori, Tarannum
Balakrishna, Nagalla
Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title_full Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title_fullStr Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title_full_unstemmed Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title_short Anterior Segment Morphology in Primary Angle Closure Glaucoma using Ultrasound Biomicroscopy
title_sort anterior segment morphology in primary angle closure glaucoma using ultrasound biomicroscopy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684238/
https://www.ncbi.nlm.nih.gov/pubmed/29151682
http://dx.doi.org/10.5005/jp-journals-10028-1230
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