Divergent roles for Clusterin in Lung Injury and Repair

Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability during lung repair. Unlike n...

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Detalles Bibliográficos
Autores principales: Habiel, David M., Camelo, Ana, Espindola, Milena, Burwell, Timothy, Hanna, Richard, Miranda, Elena, Carruthers, Alan, Bell, Matthew, Coelho, Ana Lucia, Liu, Hao, Pilataxi, Fernanda, Clarke, Lori, Grant, Ethan, Lewis, Arthur, Moore, Bethany, Knight, Darryl A., Hogaboam, Cory M., Murray, Lynne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684342/
https://www.ncbi.nlm.nih.gov/pubmed/29133960
http://dx.doi.org/10.1038/s41598-017-15670-5

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