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Site-specific phosphorylation regulates the structure and function of an intrinsically disordered domain of the glucocorticoid receptor

Intrinsically disordered (ID) regions of the transcription factor proteins have much larger frequency of phosphorylation sites than ordered regions, suggesting an important role in their regulatory capacity. Consistent with this phenomenon, most of the functionally known phosphorylation sites in the...

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Detalles Bibliográficos
Autores principales: Khan, Shagufta H., McLaughlin, William A., Kumar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684351/
https://www.ncbi.nlm.nih.gov/pubmed/29133811
http://dx.doi.org/10.1038/s41598-017-15549-5