Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway

Immunoglobulin G (IgG) is a major effector molecule of the human immune response, and aberrations in IgG glycosylation are linked to various diseases. However, the molecular mechanisms underlying protein glycosylation are still poorly understood. We present a data-driven approach to infer reactions...

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Detalles Bibliográficos
Autores principales: Benedetti, Elisa, Pučić-Baković, Maja, Keser, Toma, Wahl, Annika, Hassinen, Antti, Yang, Jeong-Yeh, Liu, Lin, Trbojević-Akmačić, Irena, Razdorov, Genadij, Štambuk, Jerko, Klarić, Lucija, Ugrina, Ivo, Selman, Maurice H. J., Wuhrer, Manfred, Rudan, Igor, Polasek, Ozren, Hayward, Caroline, Grallert, Harald, Strauch, Konstantin, Peters, Annette, Meitinger, Thomas, Gieger, Christian, Vilaj, Marija, Boons, Geert-Jan, Moremen, Kelley W., Ovchinnikova, Tatiana, Bovin, Nicolai, Kellokumpu, Sakari, Theis, Fabian J., Lauc, Gordan, Krumsiek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684356/
https://www.ncbi.nlm.nih.gov/pubmed/29133956
http://dx.doi.org/10.1038/s41467-017-01525-0

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