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Chimeric Antigen Receptor-Modified T Cells Redirected to EphA2 for the Immunotherapy of Non-Small Cell Lung Cancer

Erythropoietin-producing hepatocellular carcinoma A2 (EphA2) is overexpressed in more than 90% of non-small cell lung cancer (NSCLC) but not significantly in normal lung tissue. It is therefore an important tumor antigen target for chimeric antigen receptors (CAR)-T-based therapy in NSCLC. Here, we...

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Detalles Bibliográficos
Autores principales:	Li, Ning, Liu, Shaohui, Sun, Mingjiao, Chen, Wei, Xu, Xiaogang, Zeng, Zhu, Tang, Yemin, Dong, Yongquan, Chang, Alex H., Zhao, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684428/ https://www.ncbi.nlm.nih.gov/pubmed/29132013 http://dx.doi.org/10.1016/j.tranon.2017.10.009

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