Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer

Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme that generates NADPH to maintain reduced glutathione (GSH), which scavenges reactive oxygen species (ROS) to protect cancer cell from oxidative damage. In this study, we mainly investigate the potential roles of G6PD in colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Ju, H-Q, Lu, Y-X, Wu, Q-N, Liu, J, Zeng, Z-L, Mo, H-Y, Chen, Y, Tian, T, Wang, Y, Kang, T-B, Xie, D, Zeng, M-S, Huang, P, Xu, R-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684443/
https://www.ncbi.nlm.nih.gov/pubmed/28692052
http://dx.doi.org/10.1038/onc.2017.227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684443/
https://www.ncbi.nlm.nih.gov/pubmed/28692052
http://dx.doi.org/10.1038/onc.2017.227

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