Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy

Retroviral vectors, including those derived from gammaretroviruses and lentiviruses, have found their way into the clinical arena and demonstrated remarkable efficacy for the treatment of immunodeficiencies, leukodystrophies, and globinopathies. Despite these successes, gene therapy unfortunately al...

Descripción completa

Detalles Bibliográficos
Autores principales: Biasco, Luca, Rothe, Michael, Büning, Hildegard, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684499/
https://www.ncbi.nlm.nih.gov/pubmed/29159200
http://dx.doi.org/10.1016/j.omtm.2017.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684499/
https://www.ncbi.nlm.nih.gov/pubmed/29159200
http://dx.doi.org/10.1016/j.omtm.2017.10.002

Ejemplares similares