MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors

Age-related thymic involution is primarily induced by defects in nonhematopoietic thymic epithelial cells (TECs). It is characterized by dysfunction of multiple transcription factors (TFs), such as p63 and FoxN1, and also involves other TEC-associated regulators, such as Aire. These TFs and regulato...

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Detalles Bibliográficos
Autores principales: Xu, Minwen, Zhang, Xiaoli, Hong, Ruiyun, Su, Dong-Ming, Wang, Liefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684555/
https://www.ncbi.nlm.nih.gov/pubmed/29226156
http://dx.doi.org/10.1155/2017/2528957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684555/
https://www.ncbi.nlm.nih.gov/pubmed/29226156
http://dx.doi.org/10.1155/2017/2528957

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