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Cavity Versus Ligand Shape Descriptors: Application to Urokinase Binding Pockets
We analyzed 78 binding pockets of the human urokinase plasminogen activator (uPA) catalytic domain extracted from a data set of crystallized uPA–ligand complexes. These binding pockets were computed with an original geometric method that does NOT involve any arbitrary parameter, such as cutoff dista...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mary Ann Liebert, Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684670/ https://www.ncbi.nlm.nih.gov/pubmed/28570103 http://dx.doi.org/10.1089/cmb.2017.0061 |