Bicistronic CACNA1A Gene Expression in Neurons Derived from Spinocerebellar Ataxia Type 6 Patient-Induced Pluripotent Stem Cells

Spinocerebellar ataxia type 6 (SCA6) is an autosomal-dominant neurodegenerative disorder that is caused by a CAG trinucleotide repeat expansion in the CACNA1A gene. As one of the few bicistronic genes discovered in the human genome, CACNA1A encodes not only the α1A subunit of the P/Q type voltage-ga...

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Detalles Bibliográficos
Autores principales: Bavassano, Carlo, Eigentler, Andreas, Stanika, Ruslan, Obermair, Gerald J., Boesch, Sylvia, Dechant, Georg, Nat, Roxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684673/
https://www.ncbi.nlm.nih.gov/pubmed/28946818
http://dx.doi.org/10.1089/scd.2017.0085

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