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Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study

OBJECTIVES: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. MATERIALS AND METHODS: One hundred and fifty-one...

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Autores principales: Koul, Parvaiz A, Dar, Hilal A, Jan, Rafi A, Shah, Sanaullah, Khan, Umar Hafiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684807/
https://www.ncbi.nlm.nih.gov/pubmed/29098995
http://dx.doi.org/10.4103/lungindia.lungindia_41_17
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author Koul, Parvaiz A
Dar, Hilal A
Jan, Rafi A
Shah, Sanaullah
Khan, Umar Hafiz
author_facet Koul, Parvaiz A
Dar, Hilal A
Jan, Rafi A
Shah, Sanaullah
Khan, Umar Hafiz
author_sort Koul, Parvaiz A
collection PubMed
description OBJECTIVES: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. MATERIALS AND METHODS: One hundred and fifty-one (96 male) patients admitted for AECOPD and discharged were followed for 2 years at 3, 6, 12, 18, and 24 months for mortality. Statistical analysis was performed to identify risk factors associated with mortality. RESULTS: Sixty (39.7%) of the 151 recruited died during the 24 months of follow-up, 30 (19.8%) at 3-month, 43 (28.5%) at 6-month, 49 (32.4%) at 1-year, 55 (36.4%) at 18-month, and 60 (39.7%) at 2 years. There was no mortality in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage I (0 of 6 cases), whereas it was 12.3% (n = 8 of 65 patients) in GOLD Stage II, 41.7% (n = 15 of 36 cases), in GOLD Stage III, and 84.1% (n = 37 of 4 cases), of patients with GOLD Stage IV. Mortality was associated with 6-min walk distance, oxygen saturation, low body mass index, history of congestive heart failure, and St. George Respiratory Questionnaire score. CONCLUSION: Indian patients discharged after AECOPD have a high 2-year mortality. Measures to reduce the frequency of exacerbations need to be routinely adopted in patients with COPD.
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spelling pubmed-56848072017-11-28 Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study Koul, Parvaiz A Dar, Hilal A Jan, Rafi A Shah, Sanaullah Khan, Umar Hafiz Lung India Original Article OBJECTIVES: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. MATERIALS AND METHODS: One hundred and fifty-one (96 male) patients admitted for AECOPD and discharged were followed for 2 years at 3, 6, 12, 18, and 24 months for mortality. Statistical analysis was performed to identify risk factors associated with mortality. RESULTS: Sixty (39.7%) of the 151 recruited died during the 24 months of follow-up, 30 (19.8%) at 3-month, 43 (28.5%) at 6-month, 49 (32.4%) at 1-year, 55 (36.4%) at 18-month, and 60 (39.7%) at 2 years. There was no mortality in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage I (0 of 6 cases), whereas it was 12.3% (n = 8 of 65 patients) in GOLD Stage II, 41.7% (n = 15 of 36 cases), in GOLD Stage III, and 84.1% (n = 37 of 4 cases), of patients with GOLD Stage IV. Mortality was associated with 6-min walk distance, oxygen saturation, low body mass index, history of congestive heart failure, and St. George Respiratory Questionnaire score. CONCLUSION: Indian patients discharged after AECOPD have a high 2-year mortality. Measures to reduce the frequency of exacerbations need to be routinely adopted in patients with COPD. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5684807/ /pubmed/29098995 http://dx.doi.org/10.4103/lungindia.lungindia_41_17 Text en Copyright: © 2017 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Koul, Parvaiz A
Dar, Hilal A
Jan, Rafi A
Shah, Sanaullah
Khan, Umar Hafiz
Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title_full Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title_fullStr Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title_full_unstemmed Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title_short Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
title_sort two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: a north indian study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684807/
https://www.ncbi.nlm.nih.gov/pubmed/29098995
http://dx.doi.org/10.4103/lungindia.lungindia_41_17
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