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Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684832/ https://www.ncbi.nlm.nih.gov/pubmed/29163674 http://dx.doi.org/10.3892/etm.2017.5189 |
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author | Zhang, Hailin Li, Li Cheng, Chongjie Sun, Xiaochuan |
author_facet | Zhang, Hailin Li, Li Cheng, Chongjie Sun, Xiaochuan |
author_sort | Zhang, Hailin |
collection | PubMed |
description | Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at each point was analyzed. The results showed that, the wall shear stress (WSS) value on the top of CA1 was significantly lower than that of the top (P<0.05), the WSS value of each point on the CA2 tumor was significantly lower than that of tumor neck (P<0.05); the pressure value on the tumor top and tumor neck between CA1 and CA2 had no significant difference (P>0.05); the unsteady index of shear (UIS) value at the points of 20 had distinctly changed, the wave range was 0.6–1.5; the unsteady index of pressure value of every point was significantly lower than UIS value, the wave range was 0.25–0.40. In conclusion, the application of cerebral aneurysm hemodynamic research can help doctors to diagnose cerebral aneurysm more precisely and to grasp the opportunity of treatment during the formulating of the treatment strategies. |
format | Online Article Text |
id | pubmed-5684832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-56848322017-11-21 Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm Zhang, Hailin Li, Li Cheng, Chongjie Sun, Xiaochuan Exp Ther Med Articles Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at each point was analyzed. The results showed that, the wall shear stress (WSS) value on the top of CA1 was significantly lower than that of the top (P<0.05), the WSS value of each point on the CA2 tumor was significantly lower than that of tumor neck (P<0.05); the pressure value on the tumor top and tumor neck between CA1 and CA2 had no significant difference (P>0.05); the unsteady index of shear (UIS) value at the points of 20 had distinctly changed, the wave range was 0.6–1.5; the unsteady index of pressure value of every point was significantly lower than UIS value, the wave range was 0.25–0.40. In conclusion, the application of cerebral aneurysm hemodynamic research can help doctors to diagnose cerebral aneurysm more precisely and to grasp the opportunity of treatment during the formulating of the treatment strategies. D.A. Spandidos 2017-12 2017-09-22 /pmc/articles/PMC5684832/ /pubmed/29163674 http://dx.doi.org/10.3892/etm.2017.5189 Text en Copyright: © Zhang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Zhang, Hailin Li, Li Cheng, Chongjie Sun, Xiaochuan Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title | Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title_full | Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title_fullStr | Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title_full_unstemmed | Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title_short | Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
title_sort | clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684832/ https://www.ncbi.nlm.nih.gov/pubmed/29163674 http://dx.doi.org/10.3892/etm.2017.5189 |
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