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Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm

Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at...

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Detalles Bibliográficos
Autores principales: Zhang, Hailin, Li, Li, Cheng, Chongjie, Sun, Xiaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684832/
https://www.ncbi.nlm.nih.gov/pubmed/29163674
http://dx.doi.org/10.3892/etm.2017.5189
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author Zhang, Hailin
Li, Li
Cheng, Chongjie
Sun, Xiaochuan
author_facet Zhang, Hailin
Li, Li
Cheng, Chongjie
Sun, Xiaochuan
author_sort Zhang, Hailin
collection PubMed
description Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at each point was analyzed. The results showed that, the wall shear stress (WSS) value on the top of CA1 was significantly lower than that of the top (P<0.05), the WSS value of each point on the CA2 tumor was significantly lower than that of tumor neck (P<0.05); the pressure value on the tumor top and tumor neck between CA1 and CA2 had no significant difference (P>0.05); the unsteady index of shear (UIS) value at the points of 20 had distinctly changed, the wave range was 0.6–1.5; the unsteady index of pressure value of every point was significantly lower than UIS value, the wave range was 0.25–0.40. In conclusion, the application of cerebral aneurysm hemodynamic research can help doctors to diagnose cerebral aneurysm more precisely and to grasp the opportunity of treatment during the formulating of the treatment strategies.
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spelling pubmed-56848322017-11-21 Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm Zhang, Hailin Li, Li Cheng, Chongjie Sun, Xiaochuan Exp Ther Med Articles Our objective was to evaluate the clinical value of numerical simulation in diagnosing cerebral aneurysm based on the analysis of numerical simulation of hemodynamic model. The experimental method used was the numerical model of cerebral aneurysm hemodynamic, and the numerical value of blood flow at each point was analyzed. The results showed that, the wall shear stress (WSS) value on the top of CA1 was significantly lower than that of the top (P<0.05), the WSS value of each point on the CA2 tumor was significantly lower than that of tumor neck (P<0.05); the pressure value on the tumor top and tumor neck between CA1 and CA2 had no significant difference (P>0.05); the unsteady index of shear (UIS) value at the points of 20 had distinctly changed, the wave range was 0.6–1.5; the unsteady index of pressure value of every point was significantly lower than UIS value, the wave range was 0.25–0.40. In conclusion, the application of cerebral aneurysm hemodynamic research can help doctors to diagnose cerebral aneurysm more precisely and to grasp the opportunity of treatment during the formulating of the treatment strategies. D.A. Spandidos 2017-12 2017-09-22 /pmc/articles/PMC5684832/ /pubmed/29163674 http://dx.doi.org/10.3892/etm.2017.5189 Text en Copyright: © Zhang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Zhang, Hailin
Li, Li
Cheng, Chongjie
Sun, Xiaochuan
Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title_full Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title_fullStr Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title_full_unstemmed Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title_short Clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
title_sort clinical value of homodynamic numerical simulation applied in the treatment of cerebral aneurysm
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684832/
https://www.ncbi.nlm.nih.gov/pubmed/29163674
http://dx.doi.org/10.3892/etm.2017.5189
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