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A novel free fatty acid receptor 1 (GPR40/FFAR1) agonist, MR1704, enhances glucose‐dependent insulin secretion and improves glucose homeostasis in rats
Activation of G protein‐coupled receptor 40/Free fatty acid receptor 1 (GPR40/FFAR1), which is highly expressed in pancreatic β cells, is considered an important pharmacologic target for the treatment of type 2 diabetes mellitus. The aim of this study was to determine the effect of MR1704, a novel G...
Autores principales: | Tsuda, Naoto, Kawaji, Atsuko, Sato, Toshihiro, Takagi, Mitsuhiro, Higashi, Chika, Kato, Yutaka, Ogawa, Kumiko, Naba, Hiroyasu, Ohkouchi, Munetaka, Nakamura, Masaki, Hosaka, Yoshitaka, Sakaki, Junichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684856/ https://www.ncbi.nlm.nih.gov/pubmed/28805970 http://dx.doi.org/10.1002/prp2.340 |
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