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Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder
BACKGROUND: The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense of goal-directed control and have been objectively demonstrated using neuropsychological tests in such patients. This study...
Autores principales: | Vaghi, Matilde M., Hampshire, Adam, Fineberg, Naomi A., Kaser, Muzaffer, Brühl, Annette B., Sahakian, Barbara J., Chamberlain, Samuel R., Robbins, Trevor W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier, Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684958/ https://www.ncbi.nlm.nih.gov/pubmed/29167834 http://dx.doi.org/10.1016/j.bpsc.2017.05.005 |
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