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Autoimmune response to AGE modified human DNA: Implications in type 1 diabetes mellitus()

AIMS: Non-enzymatic glycation of DNA both in vivo and in vitro results in generation of free radicals, known as glycoxidation. Glycoxidation leads to structural perturbation of DNA resulting in generation of neo-antigenic epitopes having implication in autoimmune disorders like diabetes mellitus. In...

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Detalles Bibliográficos
Autores principales:	Ahmad, Saheem, Uddin, Moin, Habib, Safia, Shahab, Uzma, Alam, Khursheed, Ali, Asif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685016/ https://www.ncbi.nlm.nih.gov/pubmed/29159085 http://dx.doi.org/10.1016/j.jcte.2014.05.002

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