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Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)]
A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685067/ https://www.ncbi.nlm.nih.gov/pubmed/29160419 http://dx.doi.org/10.1590/1414-431X20176858 |
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author | Liu, J-C. Gu, J-J. Zhang, Y-S. |
author_facet | Liu, J-C. Gu, J-J. Zhang, Y-S. |
author_sort | Liu, J-C. |
collection | PubMed |
description | A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of the porphyrins, which is seldom seen in MPFs. In addition, in vitro anticancer activity of complex 1 on three human breast cancer cells (BT474, SKBr-3 and ZR-75-30) was further determined. |
format | Online Article Text |
id | pubmed-5685067 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Associação Brasileira de Divulgação Científica |
record_format | MEDLINE/PubMed |
spelling | pubmed-56850672017-12-01 Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] Liu, J-C. Gu, J-J. Zhang, Y-S. Braz J Med Biol Res Research Articles A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of the porphyrins, which is seldom seen in MPFs. In addition, in vitro anticancer activity of complex 1 on three human breast cancer cells (BT474, SKBr-3 and ZR-75-30) was further determined. Associação Brasileira de Divulgação Científica 2017-11-13 /pmc/articles/PMC5685067/ /pubmed/29160419 http://dx.doi.org/10.1590/1414-431X20176858 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Liu, J-C. Gu, J-J. Zhang, Y-S. Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title | Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title_full | Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title_fullStr | Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title_full_unstemmed | Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title_short | Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)(2)·(solvents)(x)] |
title_sort | synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [yk(tcpp)(oh)(2)·(solvents)(x)] |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685067/ https://www.ncbi.nlm.nih.gov/pubmed/29160419 http://dx.doi.org/10.1590/1414-431X20176858 |
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