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Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease

Ankylosing spondylitis (AS) is a common chronic immune-mediated arthropathy affecting primarily the spine and pelvis. The condition is strongly associated with HLA-B*27 as well as other human leukocyte antigen variants and at least 47 individual non-MHC-associated variants. However, substantial addi...

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Detalles Bibliográficos
Autores principales: Robinson, Philip C, Leo, Paul J, Pointon, Jennifer J, Harris, Jessica, Cremin, Katie, Bradbury, Linda A, Stebbings, Simon, Harrison, Andrew A, Duncan, Emma L, Evans, David M, Wordsworth, Paul B, Brown, Matthew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685324/
https://www.ncbi.nlm.nih.gov/pubmed/29263810
http://dx.doi.org/10.1038/npjgenmed.2016.8