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Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease
Ankylosing spondylitis (AS) is a common chronic immune-mediated arthropathy affecting primarily the spine and pelvis. The condition is strongly associated with HLA-B*27 as well as other human leukocyte antigen variants and at least 47 individual non-MHC-associated variants. However, substantial addi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685324/ https://www.ncbi.nlm.nih.gov/pubmed/29263810 http://dx.doi.org/10.1038/npjgenmed.2016.8 |