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Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease
Ankylosing spondylitis (AS) is a common chronic immune-mediated arthropathy affecting primarily the spine and pelvis. The condition is strongly associated with HLA-B*27 as well as other human leukocyte antigen variants and at least 47 individual non-MHC-associated variants. However, substantial addi...
Autores principales: | Robinson, Philip C, Leo, Paul J, Pointon, Jennifer J, Harris, Jessica, Cremin, Katie, Bradbury, Linda A, Stebbings, Simon, Harrison, Andrew A, Duncan, Emma L, Evans, David M, Wordsworth, Paul B, Brown, Matthew A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685324/ https://www.ncbi.nlm.nih.gov/pubmed/29263810 http://dx.doi.org/10.1038/npjgenmed.2016.8 |
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