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Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites

An unusual genome architecture characterizes the two related human parasitic pathogens Plasmodium falciparum and Toxoplasma gondii. A major fraction of the bulk parasite genome is packaged as transcriptionally permissive euchromatin with few loci embedded in silenced heterochromatin. Primary chromat...

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Detalles Bibliográficos
Autores principales: Sindikubwabo, Fabien, Ding, Shuai, Hussain, Tahir, Ortet, Philippe, Barakat, Mohamed, Baumgarten, Sebastian, Cannella, Dominique, Palencia, Andrés, Bougdour, Alexandre, Belmudes, Lucid, Couté, Yohann, Tardieux, Isabelle, Botté, Cyrille Y, Scherf, Artur, Hakimi, Mohamed-ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685513/
https://www.ncbi.nlm.nih.gov/pubmed/29101771
http://dx.doi.org/10.7554/eLife.29391