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Morphological adaptations in breast cancer cells as a function of prolonged passaging on compliant substrates
Standard tissue culture practices involve propagating cells on tissue culture polystyrene (TCP) dishes, which are flat, 2-dimensional (2D) and orders of magnitude stiffer than most tissues in the body. Such simplified conditions lead to phenotypical cell changes and altered cell behaviors. Hence, mu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685588/ https://www.ncbi.nlm.nih.gov/pubmed/29136040 http://dx.doi.org/10.1371/journal.pone.0187853 |