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Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

A viable vascular endothelial layer prevents vasomotor dysfunction, thrombosis, inflammation, and intimal hyperplasia. Injury to the endothelium occurs during harvest and “back table” preparation of human saphenous vein prior to implantation as an arterial bypass conduit. A subfailure overstretch mo...

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Detalles Bibliográficos
Autores principales: Komalavilas, Padmini, Luo, Weifeng, Guth, Christy M., Jolayemi, Olukemi, Bartelson, Rachel I., Cheung-Flynn, Joyce, Brophy, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685620/
https://www.ncbi.nlm.nih.gov/pubmed/29136654
http://dx.doi.org/10.1371/journal.pone.0188069

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