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SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling

SYNJ2BP plays an important role in breast cancer metastasis. However, the molecular mechanism associated with the function of SYNJ2BP in metastasis remains unclear. In this study, we investigated the role of SYNJ2BP in tumor metastasis and established the associated underlying mechanism. Over-expres...

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Detalles Bibliográficos
Autores principales:	Wang, Miao, Wu, Huijian, Li, Shujing, Xu, Zhaowei, Li, Xiahui, Yang, Yangyang, Li, Bowen, Li, Yanan, Guo, Jing, Chen, Huan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685702/ https://www.ncbi.nlm.nih.gov/pubmed/29163781 http://dx.doi.org/10.18632/oncotarget.21058

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