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MIND4-17 protects retinal pigment epithelium cells and retinal ganglion cells from UV

Nrf2 activation would efficiently protect retinal cells from UV radiation (UVR). Recent studies have developed a Nrf2-targeting thiazole-containing compound MIND4-17, which activates Nrf2 through blocking its association with Keap1. In the current study, we demonstrated that pretreatment with MIND4-...

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Detalles Bibliográficos
Autores principales: Li, Chaopeng, Yan, Kang, Wang, Wenqi, Bai, Qing, Dai, Changming, Li, Xiaofeng, Huang, Darui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685709/
https://www.ncbi.nlm.nih.gov/pubmed/29163788
http://dx.doi.org/10.18632/oncotarget.21131