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Prostaglandin E(2) and PD-1 mediated inhibition of antitumor CTL responses in the human tumor microenvironment

Accumulating evidence indicates that inflammation plays a critical role in cancer development; however, mechanisms of immunosuppression hinder productive anti-tumor immunity to limit immunopathology. Tumor-specific cytotoxic T lymphocyte (CTL) dysfunction or exhaustion by upregulating inhibitory rec...

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Detalles Bibliográficos
Autores principales:	Miao, Jie, Lu, Xu, Hu, Yuefeng, Piao, Chunmei, Wu, Xuan, Liu, Xuesong, Huang, Caiting, Wang, Yue, Li, Dan, Liu, Jingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685710/ https://www.ncbi.nlm.nih.gov/pubmed/29163789 http://dx.doi.org/10.18632/oncotarget.21155

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