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Thymine DNA Glycosylase (TDG) is involved in the pathogenesis of intestinal tumors with reduced APC expression

Thymine DNA Glycosylase (TDG) is a base excision repair enzyme that acts as a thymine and uracil DNA N-glycosylase on G:T and G:U mismatches, thus protecting CpG sites in the genome from mutagenesis by deamination. In addition, TDG has an epigenomic function by removing the novel cytosine derivative...

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Detalles Bibliográficos
Autores principales:	Xu, Jinfei, Cortellino, Salvatore, Tricarico, Rossella, Chang, Wen-Chi, Scher, Gabrielle, Devarajan, Karthik, Slifker, Michael, Moore, Robert, Bassi, Maria Rosaria, Caretti, Elena, Clapper, Margie, Cooper, Harry, Bellacosa, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685726/ https://www.ncbi.nlm.nih.gov/pubmed/29163805 http://dx.doi.org/10.18632/oncotarget.21219

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