Macitentan, a double antagonist of endothelin receptors, efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia

The crosstalk between chronic lymphocytic leukemia (CLL) cells and tumor microenvironment is essential for leukemic clone maintenance, supporting CLL cells survival, proliferation and protection from drug-induced apoptosis. Over the past years, the role of several soluble factors involved in these p...

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Detalles Bibliográficos
Autores principales: Maffei, Rossana, Fiorcari, Stefania, Vaisitti, Tiziana, Martinelli, Silvia, Benatti, Stefania, Debbia, Giulia, Rossi, Davide, Zucchini, Patrizia, Potenza, Leonardo, Luppi, Mario, Gaidano, Gianluca, Deaglio, Silvia, Marasca, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685728/
https://www.ncbi.nlm.nih.gov/pubmed/29163807
http://dx.doi.org/10.18632/oncotarget.21341

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