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Sestrin2 and sestrin3 suppress NK-92 cell-mediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC1 signaling
Ovarian cancer is one of the major cancer types. NK-92 cell line, which has consistently and reproducibly high anti-tumor cytotoxicity, may be used for immunotherapy against ovarian cancer. Understanding the mechanisms that regulate the anti-tumor activity of NK-92 cells is important for developing...
Autores principales: | Wang, Xuejin, Liu, Weifeng, Zhuang, Deyi, Hong, Shaoxian, Chen, Jingfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685737/ https://www.ncbi.nlm.nih.gov/pubmed/29163816 http://dx.doi.org/10.18632/oncotarget.21487 |
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