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Targeting cyclophilin-D by compound 19 protects neuronal cells from oxygen glucose deprivation/re-oxygenation
Oxygen and glucose deprivation (OGD) with re-oxygenation (OGDR) is applied to neuronal cells to mimic ischemia-reperfusion injuries. Activation of cyclophilin D (Cyp-D)-dependent programmed necrosis pathway mediates OGDR-induced neuronal cell damages. Here, we tested the potential effect of Compound...
Autores principales: | Zheng, Jinyu, Cui, Enhui, Yang, Haikou, Li, Mao, Zhou, Jing, Yan, Ming, Sun, Jian, Tang, De-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685745/ https://www.ncbi.nlm.nih.gov/pubmed/29163824 http://dx.doi.org/10.18632/oncotarget.21655 |
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