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Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis

Radiation therapy induces DNA damage and inflammation leading to fibrosis. Fibrosis can occur 4 to 12 months after radiation therapy. This process worsens with time and years. Radiation-induced fibrosis is characterized by fibroblasts proliferation, myofibroblast differentiation, and synthesis of co...

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Detalles Bibliográficos
Autores principales:	Vallée, Alexandre, Lecarpentier, Yves, Guillevin, Rémy, Vallée, Jean-Noël
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685775/ https://www.ncbi.nlm.nih.gov/pubmed/29163854 http://dx.doi.org/10.18632/oncotarget.21234

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