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ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments

Intracellular pathogenic microorganisms and toxins exploit host cell mechanisms to enter, exert their deleterious effects as well as hijack host nutrition for their development. A potential approach to treat multiple pathogen infections and that should not induce drug resistance is the use of small...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Pons, Valérie, Goudet, Amélie, Panigai, Laetitia, Fischer, Annette, Herweg, Jo-Ana, Kali, Sabrina, Davey, Robert A., Laporte, Jérôme, Bouclier, Céline, Yousfi, Rahima, Aubenque, Céline, Merer, Goulven, Gobbo, Emilie, Lopez, Roman, Gillet, Cynthia, Cojean, Sandrine, Popoff, Michel R., Clayette, Pascal, Le Grand, Roger, Boulogne, Claire, Tordo, Noël, Lemichez, Emmanuel, Loiseau, Philippe M., Rudel, Thomas, Sauvaire, Didier, Cintrat, Jean-Christophe, Gillet, Daniel, Barbier, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686106/
https://www.ncbi.nlm.nih.gov/pubmed/29138439
http://dx.doi.org/10.1038/s41598-017-15466-7