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US6 Gene Deletion in Herpes Simplex Virus Type 2 Enhances Dendritic Cell Function and T Cell Activation
Herpes simplex virus (HSV) type 1 (HSV-1) and type 2 (HSV-2) produce lifelong infections that are associated with frequent asymptomatic or clinically apparent reactivation. Importantly, HSV express multiple virulence factors that negatively modulate innate and adaptive immune components. Notably, HS...
Autores principales: | Retamal-Díaz, Angello, Weiss, Kayla A., Tognarelli, Eduardo I., Freire, Mariela, Bueno, Susan M., Herold, Betsy C., Jacobs, William R., González, Pablo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686121/ https://www.ncbi.nlm.nih.gov/pubmed/29176979 http://dx.doi.org/10.3389/fimmu.2017.01523 |
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