Cargando…

Drying in a microfluidic chip: experiments and simulations

We present an experimental micro-model of drying porous media, based on microfluidic cells made of arrays of pillars on a regular grid, and complement these experiments with a matching two-dimensional pore-network model of drying. Disorder, or small-scale heterogeneity, was introduced into the cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Fantinel, Paolo, Borgman, Oshri, Holtzman, Ran, Goehring, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686139/
https://www.ncbi.nlm.nih.gov/pubmed/29138494
http://dx.doi.org/10.1038/s41598-017-15718-6
_version_ 1783278725729615872
author Fantinel, Paolo
Borgman, Oshri
Holtzman, Ran
Goehring, Lucas
author_facet Fantinel, Paolo
Borgman, Oshri
Holtzman, Ran
Goehring, Lucas
author_sort Fantinel, Paolo
collection PubMed
description We present an experimental micro-model of drying porous media, based on microfluidic cells made of arrays of pillars on a regular grid, and complement these experiments with a matching two-dimensional pore-network model of drying. Disorder, or small-scale heterogeneity, was introduced into the cells by randomly varying the radii of the pillars. The microfluidic chips were filled with a volatile oil and then dried horizontally, such that gravitational effects were excluded. The experimental and simulated drying rates and patterns were then compared in detail, for various levels of disorder. The geometrical features were reproduced well, although the model under-predicted the formation of trapped clusters of drying fluid. Reproducing drying rates proved to be more challenging, but improved if the additional trapped clusters were added to the model. The methods reported can be adapted to a wide range of multi-phase flow problems, and allow for the rapid development of high-precision micro-models containing tens of thousands of individual elements.
format Online
Article
Text
id pubmed-5686139
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-56861392017-11-21 Drying in a microfluidic chip: experiments and simulations Fantinel, Paolo Borgman, Oshri Holtzman, Ran Goehring, Lucas Sci Rep Article We present an experimental micro-model of drying porous media, based on microfluidic cells made of arrays of pillars on a regular grid, and complement these experiments with a matching two-dimensional pore-network model of drying. Disorder, or small-scale heterogeneity, was introduced into the cells by randomly varying the radii of the pillars. The microfluidic chips were filled with a volatile oil and then dried horizontally, such that gravitational effects were excluded. The experimental and simulated drying rates and patterns were then compared in detail, for various levels of disorder. The geometrical features were reproduced well, although the model under-predicted the formation of trapped clusters of drying fluid. Reproducing drying rates proved to be more challenging, but improved if the additional trapped clusters were added to the model. The methods reported can be adapted to a wide range of multi-phase flow problems, and allow for the rapid development of high-precision micro-models containing tens of thousands of individual elements. Nature Publishing Group UK 2017-11-14 /pmc/articles/PMC5686139/ /pubmed/29138494 http://dx.doi.org/10.1038/s41598-017-15718-6 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Fantinel, Paolo
Borgman, Oshri
Holtzman, Ran
Goehring, Lucas
Drying in a microfluidic chip: experiments and simulations
title Drying in a microfluidic chip: experiments and simulations
title_full Drying in a microfluidic chip: experiments and simulations
title_fullStr Drying in a microfluidic chip: experiments and simulations
title_full_unstemmed Drying in a microfluidic chip: experiments and simulations
title_short Drying in a microfluidic chip: experiments and simulations
title_sort drying in a microfluidic chip: experiments and simulations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686139/
https://www.ncbi.nlm.nih.gov/pubmed/29138494
http://dx.doi.org/10.1038/s41598-017-15718-6
work_keys_str_mv AT fantinelpaolo dryinginamicrofluidicchipexperimentsandsimulations
AT borgmanoshri dryinginamicrofluidicchipexperimentsandsimulations
AT holtzmanran dryinginamicrofluidicchipexperimentsandsimulations
AT goehringlucas dryinginamicrofluidicchipexperimentsandsimulations