Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation

The high-affinity receptor for IgE expressed on the surface of mast cells and basophils interacts with antigens, via bound IgE antibody, and triggers secretion of inflammatory mediators that contribute to allergic reactions. To understand how past inputs (memory) influence future inflammatory respon...

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Detalles Bibliográficos
Autores principales: Harmon, Brooke, Chylek, Lily A., Liu, Yanli, Mitra, Eshan D., Mahajan, Avanika, Saada, Edwin A., Schudel, Benjamin R., Holowka, David A., Baird, Barbara A., Wilson, Bridget S., Hlavacek, William S., Singh, Anup K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686181/
https://www.ncbi.nlm.nih.gov/pubmed/29138425
http://dx.doi.org/10.1038/s41598-017-15568-2

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