Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside

Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is...

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Detalles Bibliográficos
Autores principales: Saburi, Ehsan, Saburi, Amin, Ghanei, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686300/
https://www.ncbi.nlm.nih.gov/pubmed/29201312
http://dx.doi.org/10.22088/cjim.8.4.228
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author Saburi, Ehsan
Saburi, Amin
Ghanei, Mostafa
author_facet Saburi, Ehsan
Saburi, Amin
Ghanei, Mostafa
author_sort Saburi, Ehsan
collection PubMed
description Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms.
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spelling pubmed-56863002017-12-01 Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside Saburi, Ehsan Saburi, Amin Ghanei, Mostafa Caspian J Intern Med Review Article Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms. Babol University of Medical Sciences 2017 /pmc/articles/PMC5686300/ /pubmed/29201312 http://dx.doi.org/10.22088/cjim.8.4.228 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Saburi, Ehsan
Saburi, Amin
Ghanei, Mostafa
Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title_full Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title_fullStr Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title_full_unstemmed Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title_short Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
title_sort promising role for gc-maf in cancer immunotherapy: from bench to bedside
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686300/
https://www.ncbi.nlm.nih.gov/pubmed/29201312
http://dx.doi.org/10.22088/cjim.8.4.228
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