Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

Multipotent adult resident cardiac stem cells (CSCs) were first identified by the expression of c-kit, the stem cell factor receptor. However, in the adult myocardium c-kit alone cannot distinguish CSCs from other c-kit-expressing (c-kit(pos)) cells. The adult heart indeed contains a heterogeneous m...

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Detalles Bibliográficos
Autores principales: Vicinanza, Carla, Aquila, Iolanda, Scalise, Mariangela, Cristiano, Francesca, Marino, Fabiola, Cianflone, Eleonora, Mancuso, Teresa, Marotta, Pina, Sacco, Walter, Lewis, Fiona C, Couch, Liam, Shone, Victoria, Gritti, Giulia, Torella, Annalaura, Smith, Andrew J, Terracciano, Cesare MN, Britti, Domenico, Veltri, Pierangelo, Indolfi, Ciro, Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M, Torella, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686347/
https://www.ncbi.nlm.nih.gov/pubmed/28800128
http://dx.doi.org/10.1038/cdd.2017.130

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