Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6

The Tyro3, Axl, and Mertk (TAM) receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in multicellular organisms. TAMs are activated by their endogenous ligands, growth arrest-specific 6 (Gas6), and protein S (Pros1), that function...

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Detalles Bibliográficos
Autores principales: Geng, Ke, Kumar, Sushil, Kimani, Stanley G., Kholodovych, Vladyslav, Kasikara, Canan, Mizuno, Kensaku, Sandiford, Oleta, Rameshwar, Pranela, Kotenko, Sergei V., Birge, Raymond B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686386/
https://www.ncbi.nlm.nih.gov/pubmed/29176978
http://dx.doi.org/10.3389/fimmu.2017.01521

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