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Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells

Aurora kinase A (AURKA) is essential for regulating mitosis and is frequently amplified in various cancer cell types. However, the effect of AURKA inhibition on the induction of apoptosis remains unclear. In the present study, it was reported that treatment with TCS7010, a specific inhibitor of AURK...

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Detalles Bibliográficos
Autores principales:	Lee, Da Hyun, Kim, Chang Gun, Lim, Yoongho, Shin, Soon Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686436/ https://www.ncbi.nlm.nih.gov/pubmed/29163689 http://dx.doi.org/10.3892/ol.2017.7023

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