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Aromatase Blockade Is Associated With Increased Mortality in Acute Illness in Male Mice

CONTEXT: The increase in circulating estrogen levels with acute illness in humans is accompanied by increased aromatase expression in adipose tissue and increased peripheral aromatization of estrogens to androgens. Animal studies indicate that estrogen may be beneficial in acute illness. OBJECTIVE:...

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Detalles Bibliográficos
Autores principales: Connerney, Jeannette J., Spratt, Daniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686622/
https://www.ncbi.nlm.nih.gov/pubmed/29264565
http://dx.doi.org/10.1210/js.2017-00128