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Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by amyloid deposition, tangle formation as well as synapse loss. Synaptic abnormalities occur early in the pathogenesis of AD. Identifying early synaptic abnormalities and their underlying mechanisms is likely important for the prevention and tre...

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Detalles Bibliográficos
Autores principales:	Bai, Yang, Li, Miao, Zhou, Yanmei, Ma, Lei, Qiao, Qian, Hu, Wanling, Li, Wei, Wills, Zachary Patrick, Gan, Wen-Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686812/ https://www.ncbi.nlm.nih.gov/pubmed/29137651 http://dx.doi.org/10.1186/s13024-017-0228-2

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