Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide

BACKGROUND: Self-renewal and differentiation of embryonic stem cells (ESCs) is directed by biological and/or physical cues that regulate multiple signaling cascades. We have previously shown that mESCs seeded in a type I collagen matrix demonstrate a loss of pluripotent marker expression and differe...

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Detalles Bibliográficos
Autores principales: Hazenbiller, Olesja, Duncan, Neil A., Krawetz, Roman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686896/
https://www.ncbi.nlm.nih.gov/pubmed/29137597
http://dx.doi.org/10.1186/s12860-017-0148-6

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