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Degradation kinetics of larotaxel and identification of its degradation products in alkaline condition
Larotaxel, a new taxane compound prepared by partial synthesis from 10-deacetyl baccatin III, is active against tumors. In this research, a selective LC–MS method was developed and validated for the study of degradation kinetics of larotaxel, which was carried out in aqueous solutions with different...
Autores principales: | Liang, Xiaoming, Liu, Zhenzhen, Shi, Huiyan, Zhang, Yuanyuan, Wang, Shixiao, Bi, Kaishun, Chen, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686960/ https://www.ncbi.nlm.nih.gov/pubmed/29404026 http://dx.doi.org/10.1016/j.jpha.2016.11.002 |
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