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Degradation kinetics of larotaxel and identification of its degradation products in alkaline condition

Larotaxel, a new taxane compound prepared by partial synthesis from 10-deacetyl baccatin III, is active against tumors. In this research, a selective LC–MS method was developed and validated for the study of degradation kinetics of larotaxel, which was carried out in aqueous solutions with different...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoming, Liu, Zhenzhen, Shi, Huiyan, Zhang, Yuanyuan, Wang, Shixiao, Bi, Kaishun, Chen, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686960/
https://www.ncbi.nlm.nih.gov/pubmed/29404026
http://dx.doi.org/10.1016/j.jpha.2016.11.002

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