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Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines

An efficient synthesis methodology for a series of tetrazolo[1,5-a]pyrimidines substituted at the 5- and 7-positions from the cyclocondensation reaction [CCC + NCN] was developed. The NCN corresponds to 5-aminotetrazole and CCC to β-enaminone. Two distinct products were observed in accordance with t...

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Detalles Bibliográficos
Autores principales: Scapin, Elisandra, Salbego, Paulo R S, Bender, Caroline R, Meyer, Alexandre R, Pagliari, Anderson B, Orlando, Tainára, Zimmer, Geórgia C, Frizzo, Clarissa P, Bonacorso, Helio G, Zanatta, Nilo, Martins, Marcos A P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687014/
https://www.ncbi.nlm.nih.gov/pubmed/29181120
http://dx.doi.org/10.3762/bjoc.13.237