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Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes
Centrosome separation along the surface of the nucleus at the onset of mitosis is critical for bipolar spindle assembly. Dynein anchored on the nuclear envelope is known to be important for centrosome separation, but it is unclear how nuclear dynein forces are organized in an anisotropic manner to p...
Autores principales: | De Simone, Alessandro, Gönczy, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687019/ https://www.ncbi.nlm.nih.gov/pubmed/28701341 http://dx.doi.org/10.1091/mbc.E16-12-0823 |
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