Cargando…

Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi

Noncentrosomal microtubule (MT) nucleation at the Golgi generates MT network asymmetry in motile vertebrate cells. Investigating the Golgi-derived MT (GDMT) distribution, we find that MT asymmetry arises from nonrandom nucleation sites at the Golgi (hotspots). Using computational simulations, we pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanders, Anna A. W. M., Chang, Kevin, Zhu, Xiaodong, Thoppil, Roslin J., Holmes, William R., Kaverina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687021/
https://www.ncbi.nlm.nih.gov/pubmed/28931596
http://dx.doi.org/10.1091/mbc.E17-06-0425