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Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi

Noncentrosomal microtubule (MT) nucleation at the Golgi generates MT network asymmetry in motile vertebrate cells. Investigating the Golgi-derived MT (GDMT) distribution, we find that MT asymmetry arises from nonrandom nucleation sites at the Golgi (hotspots). Using computational simulations, we pro...

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Detalles Bibliográficos
Autores principales:	Sanders, Anna A. W. M., Chang, Kevin, Zhu, Xiaodong, Thoppil, Roslin J., Holmes, William R., Kaverina, Irina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687021/ https://www.ncbi.nlm.nih.gov/pubmed/28931596 http://dx.doi.org/10.1091/mbc.E17-06-0425

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