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Cross-Coupling Effects of Silencing of Cyclooxygenase-2 (COX-2)/Aggrecanase-1 and Over-Expressed Insulin-Like Growth Factor 1 (IGF-1) in an Osteoarthritis Animal Model

BACKGOUND: This study aimed to observe the effect of lentivirus-mediated cyclooxygenase-2 and aggrecanase-1 silencing and insulin-like growth factor-1 overexpression in human bone marrow mesenchymal stem cells after injection into model osteoarthritic knees. MATERIAL/METHODS: Using genetic recombina...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhao, Li, Xiaofei, Huang, Heng, Wang, Guozhong, Qu, Zhigang, Zhang, Haining
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687117/ https://www.ncbi.nlm.nih.gov/pubmed/29112682 http://dx.doi.org/10.12659/MSM.907150

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